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UpToDate, the evidence-based clinical decision support resource from Wolters Kluwer, is trusted at the point of care by clinicians worldwide.INTRODUCTION. Since its clinical introduction in 1955, acetaminophen (N-acetyl-p-aminophenol; APAP; paracetamol) has become the most widely used analgesic-antipyretic in the United States [].Acetaminophen is a component of hundreds of over-the-counter and prescription medications used worldwide.…
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